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Brain Development

The human brain undergoes dramatic remodeling as it matures. Our work seeks to define normal patterns of brain development using multi-modal neuroimaging, network science, and machine learning methods.

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Hierarchical Development of Thalamo-cortical Connections

Sydnor et al. 

Nature Neuroscience

2025

BrainDevo

Translational Neuroimaging

Advances in psychiatric care are limited by our lack of understanding of the biology of these disorders. Using tools from network science and machine learning, we seek to link dysfunction in brain circuits to symptoms of mental illness such as irritability, executive dysfunction, impulsivity, and anhedonia.

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Reproducible Brain Charts for Psychiatry

Shafiei et al. 

Neuron

2025

Translation

Methods + Software

Non-invasive neuroimaging methods continue to advance at a rapid pace. We develop software and analysis methods to minimize artifact, integrate high-dimensional data, maximize reproducibility, and enhance scalability.

See our software page for further details.  

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XCP-D

Mehta & Salo et al. 

Imaging Neuroscience

2024

Methods

Lifespan Informatics and Neuroimaging Center

Richards Research Labs, 5th Floor

3700 Hamilton Walk

Philadelphia, PA 19104

Email: sattertt@pennmedicine.upenn.edu

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